''The only month in any year that might not have had a Full Moon .''
- - In Petersburg, Virginia , Confederate General Robert E. Lee begins his final offensive.
- and most of his Cabinet flee the Confederate capital of Richmond, Virginia which is taken the next day.
- April 6 - German Chemicals producer, Badische Anilin- und Sodafabrik( BASF ) founded in Mannheim .
- surrenders to Ulysses S. Grant at Appomattox , effectively ending the American Civil War.
- April 14 - US President Abraham Lincoln is assassinated by John Wilkes Booth .
- April 21 - German Chemicals producer BASF moves its headquarters and factories from Mannheim to the Hemshof District of Ludwigshafen .
- April 26
- --- Union cavalry corner John Wilkes Booth and cavalryman Boston Corbett shoots the assassin dead.
- --- General Joseph Johnston surrenders his army to General William Tecumseh Sherman at Durham Station, North Carolina .
- April 27
- --- The Steamboat '' Sultana '', carrying 2,300 passengers, explodes and sinks in the Mississippi River , killing 1,700, most of whom were Union survivors of the Andersonville Prison .
- --- Governor Of New York , Reuben Fenton , signed a bill formally creating Cornell University .
- May 1 - Triple Alliance of Argentina , Brazil and Uruguay against Paraguay is formally signed - War Of The Triple Alliance has already begun.
- , commanding all Confederate forces in Alabama , Mississippi , and eastern Louisiana , surrenders his forces to Union General E.R.S. Canby at Citronelle, Alabama .
- May 5 - In North Bend, Ohio (a suburb of Cincinnati ), the first Train Robbery in the United States takes place.
- is captured by Union troops near Irwinville, Georgia .
- - In far south Texas , more than a month after Confederate General Lee 's surrender, the last land battle of the Civil War ends with a Confederate victory.
- May 23 - Parade down Pennsylvania Ave in Washington, DC to celebrate the ending of the American Civil War .
- when an ordnance depot explodes.
- April 1 - John Milton , Governor of Florida (b. 1807 )
- April 2 - A.P. Hill , American Confederate general (b. 1825 )
- April 15 - Abraham Lincoln , 16th President Of The United States (b. 1809 )
- April 26 - John Wilkes Booth , American actor and assassin of Abraham Lincoln (b. 1838 )
- August 12 - William Jackson Hooker , English botanist (b. 1785 )
- September 2 - William Rowan Hamilton , Irish mathematician (b. 1805 )
- October 16 - Andrés Bello , Venezuelan poet, lawmaker, teacher, philosopher and sociologist (b. 1781 )
- October 18 - Lord Palmerston , Prime Minister Of The United Kingdom (b. 1784 )
- November 12 - Elizabeth Gaskell , British novelist and biographer (b. 1810 )
- November 28 - William Machin Stairs , Canadian businessman and statesman (b. 1789 )
- December 10 - Léopold I Of Belgium (b. 1790 )
- December 17 - Luigi Ciacchi , Italian cardinal (b. 1788 )
- James Barry , British military surgeon
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